# Laboratory Services for Glymphatic Study

> A sourced UK public sector contract award published by University of Exeter.

## Key facts

- Buyer: [University of Exeter](/buyers/university-of-exeter/contract-awards)
- Supplier: [Edinburgh Genetics Limited](/suppliers/edinburgh-genetics/public-sector-contract-awards)
- Award value: £100,000
- Award date: 2 February 2022
- Published: 9 February 2022
- Contract start: 2 February 2022
- Contract end: 30 September 2024
- Stage: awarded
- Procurement category: services
- Notice ID: 7781bf18-9d48-4028-9765-a0f0467f7643-508715
- OCID: ocds-b5fd17-35d4d465-4761-4a41-831d-8f04e32ac615

## Description

The main aim of this research project is to identify, in a large cohort of PD patients, relationship between the phenotype \(in motor, psychiatric, functional and cognitive symptoms, and sleep quality\) of cases of sporadic or familial forms of Parkinson's disease and AQP4 SNP genetic variations as genetic modifiers of the function of the glymphatic system\. This cross-sectional study aims at recruit up to 800 consecutive patients with PD across three large Centres in southern England\. This tender is for the blood sample analysis collected from the participants to analyse genetic variations in up to 17 SNPs of the AQP4 gene and of genetic mutations \(either pathogenic or conferring increased risk\) to a panel of 13 PD-related genes \(SNCA, PRKN, PARK7, PINK1, GBA, LRRK2, PLA2G6, FBXO7, VPS35, DNAJC6, SYNJ1, MAPT, LRP10\)\.

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## Source

[View the original notice on Contracts Finder](https://www.contractsfinder.service.gov.uk/Notice/7781bf18-9d48-4028-9765-a0f0467f7643-508715)