# C23746 - Classical Scrapie in Iceland, a model for prion diseases worldwide \(UoN\)

> A sourced UK public sector contract award published by Animal and Plant Health Agency.

## Key facts

- Buyer: [Animal and Plant Health Agency](/buyers/animal-and-plant-health-agency/contract-awards)
- Supplier: [University of Nottingham](/suppliers/university-of-nottingham/public-sector-contract-awards)
- Award value: £95,099
- Award date: 6 February 2024
- Published: 28 March 2024
- Contract start: 1 April 2023
- Contract end: 31 March 2026
- Stage: awarded
- Procurement category: services
- Notice ID: 3d0ae2b8-6c4e-4c8f-ab8e-6294454935c1-736258
- OCID: ocds-b5fd17-5ac93ae9-09ce-4845-90b1-1309ac7bf304

## Description

This STA \(single tender agreement\) approval request relates to a Research Project awarded by ICRAD to the University of Nottingham \(UoN\) following an open competition\. UoN was then jointly subcontracted with ADAS by APHA with the costs having been approved by Defra \(Project Code: SE14335\)\. The Project co-ordinator is the Friedrich-Loeffler-Institut \(FLI\), Germany\. The project involves multiple partners from 6 European countries\. The objectives of the project are to: • determine the extent of Prion protein gene \(PRNP\) variability in Icelandic sheep and predict the effect of specific polymorphisms \(PM\) on susceptibility/resistance to CS and analyse the prion biodiversity and zoonotic potential of Icelandic CS strains over time • analyse how and where scrapie infectivity remains within the environment and how effective decontamination is in the field • conduct epidemiological analysis of outbreaks to identify risk factors associated with prolonged exposure to CS, and to develop an economic model for CS response\. To address these objectives, 4 interactive Work-Packages \(WP\) were designed\. Host Genetics \(WP1\), Prion Strain Evolution \(WP2\) and Environmental Factors \(WP3\) define the key impacts on this multifactorial disease, whilst WP4 utilises all results for Epidemiological Analysis and the development of an economic model\. APHA is actively involved in WP2 \(Prion Strain Evolution\) and WP3 \(Environmental factors\)\.

## Related contract awards

- [APHA CapEx: Stereomicroscope and add-ons](/contracts/ocds-b5fd17-988c87f9-c565-4e1e-ab85-80e8566335c1) — Animal and Plant Health Agency
- [APHA Capex: Supply of Ultramicrotome](/contracts/ocds-b5fd17-7c5a8356-a2fb-4e6f-8f7a-d037a76f82d1) — Animal and Plant Health Agency
- [APHA CapEx: Supply of Portable Ultrasound](/contracts/ocds-b5fd17-e5e6318d-065e-4ed9-b1fe-ad4e22591e59) — Animal and Plant Health Agency
- [APHA Digital Audit Platform](/contracts/ocds-b5fd17-1fa62e82-42fe-497e-81ae-2e6301dea7ba) — Animal and Plant Health Agency
- [Assessment and Development of Enrichment Approaches to Enhance the Welfare of Continuously Housed Dairy Cattle](/contracts/ocds-b5fd17-105ce47d-78ab-4ff7-9860-49c18bae0ebe) — Department for Environment, Food & Rural Affairs
- [Doctorate in Clinical Psychology - Health Education England \(MIDS\)](/contracts/ocds-b5fd17-ec387cf1-bb7e-4de7-9eb4-3635751a9ca9) — NHS England
- [Snake Remotely Operated Vehicle Design and Development](/contracts/ocds-b5fd17-f260aef8-423d-4062-8eb3-4f15512f8026) — NRS Dounreay
- [RDE650 A rapid review of evidence and data of the impacts and risks on animal and human health from land and water contaminated by metals from English and Welsh abandoned metal mines\.](/contracts/ocds-b5fd17-7966e29e-34df-4eda-a51c-b53281317962) — Department for Environment, Food & Rural Affairs
- [Taxi and MPV \(1-8 seats\) Passenger Assistant - Taxi and MPV \(1-8 seats\) Passenger Assistant](/contracts/ocds-b5fd17-c807205b-b095-4dad-80ed-5eb64a2885e7) — East Sussex County Council
- [Oracle Fusion Enterprise Software](/contracts/ocds-b5fd17-b94faf4e-06c9-470e-af64-acbf9a5af410) — DEPARTMENT OF HEALTH AND SOCIAL CARE
- [National Roads Telecommunications Service 3 \(NRTS3\) Independent Assurance Review](/contracts/ocds-b5fd17-4a336c05-e4fd-4530-86b6-b037c17f1acd) — National Highways Limited
- [Taxi and MPV \(1-8 seats\) Passenger Assistant - Taxi and MPV \(1-8 seats\) Passenger Assistant](/contracts/ocds-b5fd17-63f8a7e1-2c91-4e8e-a7e9-fb3b7b757186) — East Sussex County Council

## Source

[View the original notice on Contracts Finder](https://www.contractsfinder.service.gov.uk/Notice/3d0ae2b8-6c4e-4c8f-ab8e-6294454935c1-736258)