UKRI-2399 High Specification Flow Cytometer Cell Sorter (minimum 6 lasers)

The LMB Flow Cytometry Unit wish to purchase a high specification, high throughput flow cytometer cell sorter with a minimum of 6 spatially separated lasers and a minimum of 30 fluorescence channels that is housed under a certified Class II biocontainment hood. The flow cytometer cell sorter should provide increased resolution and flexibility to sort a wide range of particles, bacteria and cell types (both primary and cultured) in various formats including 4 way or 6-way sorting, and in 96 and 384 well formats.

The goal is to provide a communal cell sorter to support research in areas of artificial biology requiring chromosome sorting for the rewriting of the human genome. Customizable options in nozzle size and pressure settings will allow purification of sensitive cell types such as neurons and single-cell organoid suspensions, facilitating downstream functional experimentation.