# Dianthus Nano System

> A sourced UK public sector contract award published by Durham University.

## Key facts

- Buyer: [Durham University](/buyers/durham-university/contract-awards)
- Supplier: NanoTemper Technologies GmbH
- Award value: £300,047
- Tender value: £300,047
- Award date: 3 January 2023
- Published: 4 January 2023
- Contract start: 17 January 2023
- Contract end: 31 March 2025
- Stage: awarded
- Procurement category: goods
- Notice ID: 9e5dc8ba-947e-4a76-beb3-62f51af45dc5-602774
- OCID: ocds-b5fd17-f9f1f317-81a5-4a57-b120-7f6c5cb5e22b

## Description

VEAT NOTICE The University has a requirement to purchase an instrument that features the latest innovation for characterising biomolecular binding affinities\. The University has published this VEAT notice and intends to award a contract to NanoTemper Technologies GmbH following the expiry of 10 days from the date of publication of this notice\. Additional information: The works, supplies or services can be provided only by a particular economic operator for the following reason: absence of competition for technical reasons Explanation: Specific features of the system include the • Measurements are performed in solution \(i\.e\. no immobilisation is required\) • Capability to quantify interactions in complex solutions \(crude extract, serum\) • Means to determine binding constant over a wide range \(5 nM - high millimolar\) as well as stoichiometry and thermodynamic parameters • Power to work at low nanomolar concentrations • Advantage of small sample volumes \(20 microliter\) coupled with the capacity to run samples in high-throughput mode using standard 384 well-plate • Used detection modalities based on two techniques: Spectral shift detection and Temperature-Related Intensity Change \(TRIC\) • Microfluidics-free • Mass independent measurement i\.e\., the measurable molecular weight range is from 101-107 Da • Measure up to 384 datapoints per run • Advantage of small sample volumes \(20 microliter\) coupled with the capacity to run samples in high-throughput mode using standard SBS 384 well-plate format

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## Source

[View the original notice on Contracts Finder](https://www.contractsfinder.service.gov.uk/Notice/9e5dc8ba-947e-4a76-beb3-62f51af45dc5-602774)
